Setting up your Epson EcoTank L3250 printer generally involves several key steps: 
Unboxing and Physical Setup, Filling the Ink Tanks, Initial Ink Charging, and Software/Wireless Setup.
1. Unpack and Prepare the Printer
Unbox: Remove the printer and all components (power cord, ink bottles, documentation, etc.) from the box.
Remove Protective Materials: Remove all tapes, films, and stabilizers from the printer exterior and scanner bed. Refer to the "Start Here" sheet for specific locations.
Connect Power: Connect the power cord to the back of the printer and to an electrical outlet. Do not turn it on yet.
Fill the Ink Tanks
Open the Ink Tank Unit: Lift the ink tank cover on the side of the printer.
Open Tank Caps: Open the cap for the first color ink tank you will fill (e.g., Black).
Prepare Ink Bottle: Unpack the corresponding ink bottle. Hold it upright and slowly twist off the cap. Do not shake or squeeze the bottle.
Fill the Tank: Insert the bottle's unique key-shaped nozzle into the printer's filling port. The ink will flow automatically and stop when the tank is full (up to the upper line). Do not squeeze the bottle.
Remove and Cap: When the ink flow stops, remove the bottle and securely replace the ink tank cap. If there is leftover ink, securely replace the bottle cap and store it upright.
Repeat: Repeat this process for all remaining colors.
Close Cover: Securely close the ink tank cover.
3. Initial Ink Charging
Turn On: Press the power button to turn the printer on. The power light will likely start flashing.
Start Charging: Wait until the ink droplet light (often next to the paper light) turns orange. Then, press and hold the Stop button (the button with a circle and triangle) for about 5 seconds.
Wait: The printer will start the initial ink charging process. The power light will blink. This process takes about 10 to 11 minutes.
Do Not Interrupt: Do not turn off the printer or open the ink tank cover during this time, as it can damage the print head.
Charging Complete: The charging is complete when the power light stops blinking and stays green, and the ink droplet and paper lights turn off.
4. Load Paper and Install Software
Load Paper: Flip the feeder guard forward, raise the paper support, and slide the edge guides all the way out. Load plain paper (Letter or A4 size) in the rear paper feeder.
Install Software: The easiest way to complete the setup, especially for Wi-Fi, is using a mobile device:
Mobile Setup (Recommended): Download the Epson Smart Panel app on your smartphone or tablet. Open the app and follow the on-screen instructions to connect the printer to your Wi-Fi network and install the necessary drivers.
Computer Setup: Go to the official Epson support website for the L3250, select your operating system, and download the recommended driver and utility package. Run the installer and follow the prompts to connect the printer to your computer (either via a USB cable initially or directly via Wi-Fi during the setup process).
Once the software is installed and the printer is connected, it should be ready to print! You may want to run a test print or nozzle check from the software or app to confirm everything is working correctly.